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Bystander effect (radiobiology) The radiation-induced bystander effect (bystander effect) is the phenomenon in which non irradiated cells exhibit irradiated effects as a result of signals received from nearby irradiated cells.

Direct and indirect effects of exposure to 900 MHz GSM RF EMF on CHO cell line:
Evidence of bystander effect by non-ionizing radiation
Jooyan N, Goliaei B, Bigdeli B, Faraji-Dana R, Zamani A, Entezami M, Mortazavi SMJ.


Direct and indirect effects of exposure to 900 MHz GSM radiofrequency electromagnetic fields on CHO cell line: Evidence of
bystander effect by non-ionizing radiation. Environ Res. 2019 Apr 1. pii: S0013-9351(19)30197-5. doi:
10.1016/j.envres.2019.03.063.


Highlights
• Short-term exposure to radiofrequency radiation (RFR) emitted from mobile phones may cause genotoxic effects.
• RFR has both targeted and non-targeted effects on cells.
• RFR-induced non-targeted effects include bystander effect.
• The biological effects of RFR are possibly mediated by oxidative stress.
• Extracellular ROS can trigger molecular signals in non-targeted cells.
Abstract
INTRODUCTION: The rapid rise in global concerns about the adverse health effects of exposure to radiofrequency radiation (RFR) generated by common devices such as mobile phones has prompted scientists to further investigate the biological effects of these environmental exposures.

Non-targeted effects (NTEs) are responses which do not need a direct exposure to be expressed and are particularly significant at low energy
radiations. Although NTEs of ionizing radiation are well documented, there are scarcely any studies on non- targeted responses such as bystander effect (BE) after exposure to non-ionizing radiation. The main goal of
this research is to study possible RFR-induced BE.

https://www.ncbi.nlm.nih.gov/pubmed/31036329

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